SIG | Developmental and Epileptic Encephalopathies (DEE): Moving from a Seizure-Centric to a Holistic Evaluation of DEE Patients

Monday, December 6, 2021
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OVERVIEW: 

This Special Interest Group features a holistic approach to the evaluation of Developmental and Epileptic Encephalopathies.  

Developmental and Epileptic Encephalopathies (DEEs) are among the most severe epilepsies. The management of the DEEs extends beyond just treatment of seizures, as these epilepsies are associated with severe comorbidities and high risk of mortality. It is about time to leave the seizure-centric approach to DEEs and explore how a holistic evaluation and treatment may affect patient outcomes.  

In this SIG, a panel of experts explore the complex relationship between seizure control and comorbidities in DEEs and the potential impact of seizure control. Speakers review what can be learned from animal models of DEEs and how to apply this knowledge to patient care. The conversation concludes with a discussion on the role of natural history studies and what they are teaching this community of care providers.

Learning Objectives:

Following participation in this activity, participants will be able to: 

  • Define the scope of symptoms in DEEs and the impact of seizure control on comorbidities 
  • Describe the non-seizure outcomes in animal models of DEE 
  • Demonstrate the adult outcomes of DEEs as seen in natural history studies of these conditions

Program:

SIG Coordinators: Elaine Wirrell, MD, Danielle Andrade MD, MSc, FRCPC, CSCN, and Anthony Fine, MD 

Chair: Elaine Wirrell, MD 

What is the Evidence that Earlier and More Complete Seizure Control Improves Comorbidities in DEEs? | Anthony Fine, MD 

What Can Animal Models Teach Us about Outcomes? | Lori Isom, PhD, FAES 

What are the Issues with DEE? Stay the Course or Aggressively Investigate and Treat? | Danielle Andrade, MD, MSc, FRCPC, CSCN 

Education Credit:

1.5 Nursing Contact Hours 

1.5 Pharmacy Contact Hours 

1.5 CME 

This educational activity is supported in part by education grants from: Stoke Therapeutics. 

Activity Type
Special Interest Group
Credit
CME
CE
Format
In person
On-demand
Career Stage
Early Career (typically 0-5 years from completion of training)
Mid-Career (typically 6-15 years from completion of training)
Senior (typically >15 years from completion of training)
Audience
Advocates
Advanced Practice Providers
Behavioral Health Providers
Clinicians
Fellows/Trainees
Nurses
Pharmacists
Scientists/Researchers
Technicians
Demographic
Clinical
First-time Attendees
Research
Young Professionals