SIG | Epilepsy and Aging: Late-Onset Epilepsy–A Unique Clinical Entity
Saturday, December 4, 2021
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OVERVIEW:
New-onset epilepsy disproportionately affects older adults and can be difficult to diagnose. Since older adults represent one of the fastest growing segments of our population, there is a pressing need to better define late-onset epilepsy. This session focuses on demographical, clinical, neuroimaging, and animal model evidence that suggests that late-onset epilepsy may be a unique disease phenomenon.
Speakers review:
- The latest data on machine learning-based identification of clinical features that separate late-onset epilepsy from early- and adult-onset epilepsies and discuss the incidence and prevalence of epilepsy in the aging population
- Modifiable (cardiovascular, dietary, etc.) and non-modifiable (genetic susceptibility) risk factors that describe neuroimaging findings unique to late-onset epilepsies using structural and functional imaging modalities as the recognition of such clinical and neuroimaging features are critical for the identification of at-risk individuals, timely diagnosis, and treatment of our older patientsI
- Insights from animal models, with emphasis on electrophysiological studies that identify novel features and potential biomarkers that will be critical for early diagnosis and mechanism-based therapies
Three distinguished speakers address these topics, representing a spectrum of clinical and basic science expertise. Presenters provide case study examples and new research findings. Clinical and basic researchers will gain valuable information about late-onset epilepsy.
Learning Objectives:
Following participation in this activity, participants will be able to:
- Define the clinical characteristics of late-onset epilepsy that distinguish it from early- and adult-onset epilepsy
- Describe the contributions of modifiable and non-modifiable risk factors to the incidence of late-onset epilepsy
- Describe the electrophysiological features identified in animal models that may serve as novel biomarkers for early diagnosis and benchmarks for therapeutic development
Program:
SIG Coordinators: Jeannie Chin, PhD, Vineet Punia, MD, MS, and Keith Vossel, MD, MSc
Chair: Jeannie Chin, PhD
Co-Chair: Vineet Punia, MD, MS
Defining Late-Onset Epilepsy | Colin Josephson, MD, MSc, FRCP(C), CSCN
Modifiable and Non-Modifiable Risk Factors in Late-Onset Epilepsy | Emily Johnson, MD
Diagnostic and Therapeutic Strategies for Late-Onset Epilepsy – Insights from Animal Models | Jerome Engel, Jr., MD, PhD
Education Credit:
1.5 Nursing Contact Hours
1.5 Pharmacy Contact Hours
1.5 CME