Investigators Workshop | Memory Mechanisms in the Epileptic Brain

OVERVIEW:

This session explores ways to improve memory and cognition in temporal lobe epilepsy.  

Patients with temporal lobe epilepsy can experience difficulties with their memory. There has been rapid growth in the understanding of fundamental mechanisms of hippocampal memory storage and consolidation. These studies point to distinctive roles for various structures, which interact through network oscillations such as the theta rhythm, sharp wave-ripples, slow neocortical oscillations (up-down states), and sleep spindles. Furthermore, a growing number of studies demonstrate how structural and functional pathology of temporal lobe epilepsy disrupts memory formation and consolidation. The workshop features emerging leaders in the study of memory disruption in temporal lobe epilepsy and seeks to stimulate further research in this area.