SIG │ Neuropharmacology: Managing Breakthrough Seizures–An Art or Science?
Tuesday, December 7, 2021
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OVERVIEW:
This Special Interest Group addresses the nuanced management of breakthrough seizures.
Two-thirds of people with epilepsy experience seizure-freedom with optimization of antiseizure medications. Breakthrough seizures interrupt the seizure-freedom in a subset of these patients and pose the threat of injuries, unemployment, sudden death, and increased health care costs. Management of breakthrough seizures is of paramount importance in maintaining seizure-freedom in medically responsive epilepsy. However, this continues to be a challenge to health care teams. Several factors including medication nonadherence and drug-drug interactions could be the underlying etiology of breakthrough seizures.
In this SIG, speakers delve deeper into understanding medication nonadherence and utilization of drug monitoring and explore typical to rare drug interactions.
Case-based learning is used to illustrate discussion points. The speakers prepare a case and create questions for the audience to actively participate using audience polling tools. The use of the poll feature enables presenters and audiences to assess the knowledge level before and after the session as well as their knowledge improvement.
Learning Objectives:
Following participation in this activity, participants will be able to:
- Define non-adherence and classify different types of nonadherence. List strategies to deal with non-adherence
- Recognize common, uncommon, and rare drug-drug interactions that might affect level of anti-seizure medications
- Analyze the use of anti-seizure drug monitoring while dealing with breakthrough seizures
Program:
SIG Coordinators: Annaporna Bhat, MD, PhD, Mindl Weingarten, PharmD, BCPPS, and Proletta Datta, MD, PhD
Chair: Annaporna Bhat, MD, PhD
Antiseizure Medication Non-Adherence | Derek Bauer, MD
Drug-Dug Interactions – Common, Uncommon, and Rare | Andrea Calvert, PharmD, BCPPS
Antiseizure Medication Drug Monitoring – Pros, Cons, and Pitfalls | Sasha Alick-Lindstrom, MD