SIG | Critical Care: An Update on NORSE and FIRES

Friday, December 3, 2021
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OVERVIEW:

This year's Critical Care Special Interest Group focuses on the management of NORSE/FIRES in the intensive care unit (ICU).

New Onset Refractory Status Epilepticus (NORSE) and the subcategory Febrile Infection-Related Epilepsy Syndrome (FIRES) are increasingly recognized clinically and the focus of bench and clinical research. This year's SIG focuses on the ICU management of NORSE/FIRES, including discussions of both mechanisms and optimal treatment approaches in the absence of definitive evidence. The SIG features three junior or trainee members presenting high-rated abstracts related to Critical Care Epilepsy.

Learning Objectives:

Following participation in this activity, participants will be able to:

  • Summarize the proposed pathogenic mechanisms of seizures in NORSE and FIRES and review the relevant evidence-based literature
  • Describe immune modulatory treatment options for NORSE and FIRES that target the proposed abnormal autoinflammation
  • Provide guidance for rapid diagnosis and timely initiation of appropriate treatment for NORSE/FIRES

Program:

SIG Coordinators: Courtney Wusthoff, MD, MS, FAES, Hiba Haider, MD, FAES, and Nicholas Abend, MD, MSCE, FAES

Chair: Courtney Wusthoff, MD, MS, FAES

Co-Chair: Hiba Haider, MD, FAES

Data Blitz: Selected Posters from the Annual Meeting:

Ketamine Administration without Coma Induction in the Emergency Setting | Megan E. Barra, PharmD 

Stimulus-Induced, Rhythmic, Periodic, or Ictal Discharges (SIRPIDs): To Treat or Not to Treat? | Andrew Christiana, MD 

Does Insurance Status Influence Inpatient Outcomes in Patients Admitted with Status Epilepticus? | Maryam Syed, MBBS 

Advances in NORSE and FIRES:  

Advances in Understanding Pathogenic Mechanisms of Persistent Seizures in NORSE and FIRES | Olga Taraschenko, MD, PhD 

Targeting the Abnormal Inflammatory Response in NORSE and FIRES: Anakinra and Others | Krista Eschbach, MD 

Diagnosis and Treatment of NORSE/FIRES - A Consensus Approach | Ronny Wickström, MD, PhD 

Education Credit:

1.5 Nursing Contact Hours 

1.5 Pharmacy Contact Hours 

1.5 CME 

Activity Type
Special Interest Group
Credit
CME
CE
Format
In person
On-demand
Career Stage
Early Career (typically 0-5 years from completion of training)
Mid-Career (typically 6-15 years from completion of training)
Senior (typically >15 years from completion of training)
Audience
Advocates
Advanced Practice Providers
Behavioral Health Providers
Clinicians
Fellows/Trainees
Nurses
Pharmacists
Scientists/Researchers
Technicians
Demographic
Clinical
Research