Investigators Workshop | Therapeutic Benefits of Targeting Neuropeptides in Epilepsy
Sunday, December 5, 2021
-
You may need to log in to view video on this page.
OVERVIEW:
Neuropeptides have long been known to be key modulators of neurological function. Moreover, several key neuropeptides have been identified as playing an important role in epilepsy pathophysiology.
Basic science and translational research in this field suggest the continued potential for neuropeptides and their receptors as targets for therapy development. This workshop will highlight recent advances in neuropeptide therapy development in general and will focus on specific examples that demonstrate potential avenues for future and ongoing efforts.
Learning Objectives:
Following participation in this activity, participants will be able to:
- Describe the role of neuropeptides in the pathophysiology of epilepsy and as potential therapeutic targets
- Explain the mechanism of action of selected (discussed) neuropeptides including galanin, NPY, and oxytocin
- Explain the challenges to targeting neuropeptides for antiseizure or disease-modifying therapy, as well as recent advances that may overcome these challenges
Program:
Moderators: Cameron S. Metcalf, PhD and Jennifer Wong, PhD
Speakers: Cameron S. Metcalf, PhD, Jennifer Wong, PhD, and Esbjörn Melin, PhD