Investigators Workshop | Neurodegeneration in Epilepsy

Friday, December 3, 2021
-

You may need to log in to view video on this page.

OVERVIEW:

This workshop addresses the intersection of epilepsy, neurodegeneration, and cognition.

Epilepsy is conceptualized as a disorder affecting widespread brain networks. Recent neuroimaging studies detected abnormalities dynamically spreading from the epileptic focus into both hemispheres through interconnected network hubs, even in the absence of seizures. Neuropathology characterized these changes as neuronal loss, inflammation, and accumulation of Beta-Amyloid and phosphorylated Tau. The degree of Tau accumulation correlates with cognition.

This workshop explores the risk of older adults with developing dementia and the bi-directional relationship between neurodegeneration in dementia and epilepsy

Learning Objectives:

Following participation in this activity, participants will be able to:

  • Recognize the risk factors and spatial extent of widespread network disturbances in epilepsy based on neuroimaging findings
  • Define the mechanisms of neurodegeneration in epilepsy from insights in neuropathology
  • Discuss the trajectories of cognitive decline in late onset epilepsy and the predictors of developing dementia in older adults with epilepsy

Program:

Moderators: Marian Galovic, MD and Emily Johnson, MD

Speakers: Marian Galovic, MD, Emily Johnson, MD, and Maria Thom, MD, MBBS

Activity Type
Investigators Workshop
Credit
Non-CME
Format
In person
Career Stage
Early Career (typically 0-5 years from completion of training)
Mid-Career (typically 6-15 years from completion of training)
Senior (typically >15 years from completion of training)
Audience
Clinicians
Fellows/Trainees
Scientists/Researchers
Technicians
Demographic
Clinical
Research