Basic Science Skills Workshop | Stem Cell-Derived Brain Organoid Approaches for Epilepsy Research

Friday, December 3, 2021
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OVERVIEW :

This workshop presents the current state of stem cell-derived human brain organoid technologies with a focus on their use in epilepsy research.  

Over the past decade, substantial gains have been made in differentiating stem cells into self-assembled three-dimensional structures (brain organoids) that recapitulate many features of the developing human brain. Brain organoids are emerging as a powerful experimental tool for modeling neurological diseases including epilepsy. 

Presenters review multiple approaches available to generate human brain organoids, as well as the experimental design considerations important for guiding disease modeling studies.  

This workshop examines: 

  1. The strengths and weaknesses of the approach for modeling epilepsy 
  2. Key insights in the epilepsy field from current literature 
  3. A look forward to next generation advances and the future of this exciting and rapidly advancing field

Learning Objectives:

Following participation in this activity, participants will be able to: 

  • Describe the current techniques for modeling epilepsy using human brain organoids 
  • Evaluate the strengths and weaknesses of different human brain organoid approaches for modeling epilepsy 

Program:

Chair: Christopher Makinson, PhD 

Speakers: Giorgia Quadrato, PhD and Alex Shcheglovitov, PhD 

Activity Type
Skills Workshop
Credit
Non-CME
Format
In person
On-demand
Career Stage
Early Career (typically 0-5 years from completion of training)
Mid-Career (typically 6-15 years from completion of training)
Audience
Fellows/Trainees
Scientists/Researchers
Technicians
Demographic
Research
First-time Attendees
Young Professionals